What are the most effective drugs to cure hepatites c type 1a?
Female age 35 of african origin. diagnosis grade one
What are the most effective drugs to cure hepatites c type 1a?managed c++
Current standard of care treatment is a combination of (pegylated) interferon alpha and the antiviral drug ribavirin for a period of 24 or 48 weeks, depending on genotype. Should treatment with pegylated ribivirin-interferon not return a 2-log viral reduction after 12 weeks, the chance of treatment success is less than 1%. Current indication for treatment include patients with proven hepatitis C virus infection and persistent abnormal liver function tests. Sustained cure rates (sustained viral response) of 75% or better occur in people with genotypes HCV 2 and 3 in 24 weeks of treatment, about 50% in those with genotype 1 with 48 weeks of treatment and 65% for those with genotype 4 in 48 weeks of treatment. About 80% of hepatitis C patients in the United State have genotype 1. Genotype 4 is more common in the Middle East and Africa.
Treatment during the acute infection phase has much higher success rates (90%+) with a shorter duration of treatment.
Those with low initial viral loads respond much better to treatment than those with higher viral loads (>2 million virons/ml). Current combination therapy can only be supervised by physicians in the fields of gastroenterology, hepatology and infectious disease.
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